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Obesity as comparedwith physical activity in predicting risk of coronaryheart disease in women. Once cAMP production was stopped there was a decrease of ICER andincrease in the translocation of NFATc1 to the nucleus, which induced T cell proliferation.The proliferation of Tregs in this situation was independent of TCR engagement, but wasdependent on minute amounts of exogenous IL-2 (Klein 2013)
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